Our mission is to develop multidisciplinary approaches for natural products research and increasing the efficiency of biological control agents (for crop protection) and therapeutics (for human disease) discovery. The promise of unprecedented structural diversity and potent biological activity from natural products remained powerful forces driving therapeutics discovery. We have incorporated in situ metabolomics (imaging mass spectrometry), comparative metabolomics (molecular networking) and genome/transcriptome mining as an integrated strategy for microbial natural products research. The output would lead us to understand the progression and mechanisms of agricultural diseases. We anticipate that through such investigations we will be able to develop new therapeutic leads or new biological control methods.
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